INFLAMMATION-DRIVEN BONE LOSS IN PSORIASIS: ASSOCIATION WITH CYTOKINE PROFILE AND VITAMIN D DEFICIENCY
Abstract
To investigate bone mineral density (BMD) and metabolic disturbances in patients with psoriasis, and to evaluate the relationship between bone turnover markers, disease severity, and cytokine profile.
References
1. Galluzzo M. et al. Bone metabolism in psoriasis: a review. J Eur Acad Dermatol
Venereol. 2020;34(9):2039–2047.
2. Ryan C. et al. Psoriasis and bone mineral density: a cross-sectional study. Clin Exp
Dermatol. 2021;46(7):1253–1260.
3. Giustina A. et al. Vitamin D and chronic inflammatory skin disorders. Front Immunol.
2019;10:1939.
4. Wu W. et al. Inflammation and bone loss in psoriasis: molecular mechanisms. Int J Mol Sci. 2023 [11]). Giunta A. и соавт. 2022;23(5):2763.
5. Kumar S. et al. Cytokine imbalance and bone metabolism in psoriasis. Clin Rheumatol. 2018;37(10):2719–2725.
6. Menter A. et al. Psoriasis as a systemic inflammatory disease. Br J Dermatol. 2019;180(5):875–883.
7. Федотова Н.В. и соавт. Костно-метаболические нарушения при хронических дерматозах. Вестник дерматологии. 2021;97(4):22–28.
8. Krajewska-Włodarczyk M. et al. Bone mineral density in psoriasis. J Clin Med. 2020;9(10):3156.
9. Ocampo D.V., Gladman D.D. Psoriatic disease and the bone. Curr Rheumatol Rep. 2022;24(2):45–52.
10. Gisondi P. et al. Vitamin D and inflammatory skin diseases. J Steroid Biochem Mol Biol. 2021;204:105754.
11. Giunta A. et al. Effects of IL‑17 inhibition on bone metabolism. Dermatol Ther.
2023;36(2):e15678.
12. Chandran V. et al. Osteoimmunology in psoriatic disease. Nat Rev Rheumatol.
2023;19(1):41–55.
13. Egeberg A. et al. Epidemiology of osteoporosis in psoriasis. J Eur Acad Dermatol
Venereol. 2020;34(12):2808–2816.14. Capsoni F. et al. Vitamin D receptor pathways in psoriasis. Exp Dermatol.
2022;31(5):638–646.
15. McInnes I.B. et al. Cytokine signaling and bone remodeling. Nat Rev Immunol.2024;24(3):155–170.
