ETIOLOGICAL FACTORS AND PATHOGENETIC MECHANISMS OF SECONDARY DENTAL DEFORMATIONS: A SYSTEMATIC REVIEW
Abstract
Background. Secondary dental deformations (SDD) develop as a result of complex interactions between local biomechanical triggers, inflammatory biological processes, and systemic modulating factors. Despite their high prevalence — affecting 40–65% of adult patients with partial edentulism — the etiological hierarchy and pathogenetic cascades underlying SDD remain incompletely characterized in an integrated framework. A systematic synthesis of available molecular, biomechanical, and epidemiological evidence is therefore needed.
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