INFLAMMATORY-IMMUNE AND METABOLIC PREDICTORS OF STRUCTURAL AND FUNCTIONAL CHANGES IN THE MYOCARDIUM AND DAILY PRESSURE PROFILE IN PATIENTS WITH RHEUMATOID ARTHRITIS
Abstract
Cardiovascular diseases continue to occupy leading positions in the structure of general mortality and disability of the population, while arterial hypertension is considered one of the main modifiable risk factors for the development of adverse cardiovascular outcomes [5, 15]. Modern understanding of the pathogenesis of arterial hypertension extends beyond isolated hemodynamic disorders and increasingly emphasizes the role of systemic inflammation, immune dysfunction, and metabolic disorders in the formation of target organ damage, including the heart [2].
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