CLINICAL AND PHARMACOLOGICAL ASPECTS OF THERAPY FOR ELDERLY PATIENTS
Abstract
Arterial hypertension (HTN) remains a leading cause of morbidity, disability , and mortality in most countries worldwide. A significant proportion of patients with hypertension are elderly, and treating it in them is associated with a number of challenges: high comorbidity , more frequent adverse reactions to medication, and poor adherence to treatment. Achieving target blood pressure levels in these patients often requires the use of two or more medications, which significantly complicates treatment and reduces adherence. The article examines the clinical and pharmacological features of therapy for elderly patients, taking into account age-related changes in organs and systems that affect the pharmacokinetics and pharmacodynamics of drugs.
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