PATHOMORPHOLOGICAL BASIS OF ADRENAL GLAND AND THYMUS DISINTEGRATION IN PRETERM STILLBORN INFANTS: A CASE STUDY OF FERGANA REGION

Bakhramjon Vakhidjonovich Qochqarov

Authors

Bakhramjon Vakhidjonovich Qochqarov Author

Abstract

Preterm stillbirth remains one of the major challenges of modern perinatal medicine due to its high contribution to perinatal mortality and the complexity of the underlying pathogenetic mechanisms. Among the organs most sensitive to intrauterine stress and hypoxic damage are the adrenal glands and thymus, which play crucial roles in endocrine regulation, stress adaptation, and immune system development during fetal life. The present study aimed to investigate the pathomorphological features of adrenal gland and thymus disintegration in preterm stillborn infants using materials obtained from the Fergana region. A retrospective morphological analysis was performed on autopsy specimens collected from preterm stillborn infants of different gestational ages. Macroscopic and microscopic examinations were carried out using conventional histological techniques, including hematoxylin and eosin staining.

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