IMPACT OF METABOLIC SYNDROME ON ANESTHESIA COURSE AND PERIOPERATIVE OUTCOMES IN SURGICAL PATIENTS

Authors

  • Kamalov Farkhod Zuhriddinovich Author

Abstract

Metabolic syndrome is one of the most significant risk factors for perioperative complications in patients undergoing anesthesia. The combination of abdominal obesity, insulin resistance, arterial hypertension, and dyslipidemia creates an adverse metabolic background that significantly affects the pharmacokinetics and pharmacodynamics of anesthetic agents, hemodynamic stability, and the incidence of postoperative complications.

References

1. Alberti K.G. et al. Harmonizing the metabolic syndrome. Circulation, 2009.

2. International Diabetes Federation (IDF). Worldwide definition of the metabolic syndrome, 2006.

3. Reaven G.M. Role of insulin resistance in human disease. Diabetes, 1988.

4. McNeill A.M. et al. Metabolic syndrome and perioperative risk. Anesthesiology, 2012.

5. Polderman K.H. et al. Perioperative hemodynamic management. Critical Care, 2019.

6. Vincent J.L. Microcirculation in critical illness. Critical Care, 2018.

7. Kuziev O.A., Ibragimov N.K., Mamatov B.Yu., Ismailov O.A., Ramazanova Z.F. Assessment of liver functional state in patients with acute kidney injury caused by blood loss during childbirth. NMP, 2025;(4). Available at: https://cyberleninka.ru/article/n/otsenka-funktsionalnogo-sostoyaniya-pecheni-u-bolnyh-s-ostrym-pochechnym-porazheniem-vyzvannym-krovopoterey-vo-vremya-rodov (accessed 04.06.2026).

8. Saugel B. Hemodynamic monitoring in anesthesia. Br J Anaesth, 2020.

9. Mikhail M.S. Metabolic syndrome and anesthesia risk. Anesth Analg, 2017.

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Published

2026-06-07