THE EFFECT OF L-TYPE CALCIUM CHANNEL BLOCKERS ON AORTIC TONE
Abstract
The article presents modern concepts of the pathogenesis of arterial hypertension, its leading role in the development of cardiovascular diseases, and mechanisms associated with impaired calcium ion metabolism in vascular smooth muscle cells. Key factors in the development of hypertension, including increased tone of the aorta and large arteries, enhanced activity of L-type calcium channels, and alterations in endothelium-dependent vasoregulatory processes, are analyzed..
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