CORRELATION BETWEEN ENDOSCOPIC AND MORPHOLOGICAL DIAGNOSIS OF COLONIC ADENOCARCINOMA: EPIDEMIOLOGICAL TRENDS AND SCREENING-BASED ASSESSMENT IN UZBEKISTAN

Gulmira Bazarbaeva Azimjonovna

Authors

Gulmira Bazarbaeva Azimjonovna Author

Abstract

Colonic adenocarcinoma represents the predominant histological subtype of colorectal cancer and remains a leading cause of cancer-related morbidity and mortality worldwide. Accurate diagnosis requires a close correlation between endoscopic visualization and morphological verification, as each modality provides complementary information regarding tumor localization, macroscopic features, and histopathological characteristics. The present theoretical-analytical study explores the correlation between endoscopic and morphological diagnostic findings in colonic adenocarcinoma, while simultaneously examining epidemiological tendencies, risk factors, age distribution, and the role of screening programs, with particular emphasis on Uzbekistan. Based on the synthesis of international scientific literature, epidemiological databases, and regional oncological reports, this study demonstrates that combined endoscopic and histopathological evaluation significantly enhances diagnostic accuracy, early-stage detection, and appropriate clinical stratification. A strong correlation between endoscopic appearance and histological grade has been documented, supporting the feasibility of risk stratification during colonoscopy. Strengthening population-based screening, expanding access to high-quality endoscopy, and standardizing pathology reporting are identified as critical priorities. This work underscores the necessity of integrated diagnostic approaches and evidence-based screening strategies to reduce disease burden and improve survival outcomes in Uzbekistan.

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