IN PATIENTS WITH UAS OBSERVED, THE INCIDENCE OF LABARATOR INDICATORS BY SEX
Abstract
The results of the study showed that laboratory, hormonal, and metabolic parameters in patients with spinal artery syndrome (ALS) vary depending on gender and stage of the disease. In women, hemostasis parameters in the functional stage were mostly maintained normally, while in the organic stage of APTT, an increase in prothrombin time and INR, an increase in fibrinogen and a decrease in antithrombin III indicated activation of thrombogenic and inflammatory processes.; In men, these changes were more pronounced, harmonized with hemostasis and platelet imbalance. and hemodynamic disorders. Elevated levels of hormonal and inflammatory markers in women are associated with cognitive and psychoemotional disorders. At the same time, statistically significant differences were found in the indicators of estrogen, testosterone, progesterone, HOMA-IR, cortisol, and vitamin D depending on the stage of the disease and the psychotype, with a relative norm in the functional stage and a deepening of hormonal and metabolic imbalance in the organic stage (p<0.01). The results obtained confirm the need for individual diagnostic and therapeutic approaches, taking into account the gender and stage of the disease in ALS patients.
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