OPTIMIZATION OF DIAGNOSTIC AND THERAPEUTIC METHODS FOR OBSTRUCTIVE BRONCHITIS IN CHILDREN WITH ALLERGIC DISEASES

Sayyora Rustamovna Safarova

Authors

Sayyora Rustamovna Safarova Author

Abstract

Obstructive bronchitis is a common respiratory condition in children, often exacerbated by underlying allergic diseases. This article explores advanced diagnostic and therapeutic strategies tailored for pediatric patients with this comorbidity. A prospective study involving 100 children aged 5–12 years was conducted, employing allergen-specific IgE analysis, pulmonary function tests, and clinical assessments to refine diagnostic accuracy. Therapeutic protocols included pharmacological and non-pharmacological approaches such as antihistamines, inhaled corticosteroids, and allergen avoidance strategies. Results demonstrated a 75% improvement in clinical symptoms and a 40% reduction in hospitalizations with personalized treatment plans. This study highlights the critical need for integrated care models in pediatric obstructive bronchitis.

References

1. Gupta, A., et al. Pediatric Allergy and Pulmonology: An Integrated Approach. Springer, 2022.

2. World Health Organization (WHO). Guidelines for Managing Pediatric Respiratory Diseases. WHO Publications, 2023.

3. Johnson, T., et al. "Advances in Obstructive Bronchitis Management in Pediatrics," Journal of Pediatric Medicine, vol. 18, no. 3, pp. 145–157, 2021.

4. American Thoracic Society. Pulmonary Function Testing Standards. ATS Guidelines, 2023.

5. Martinez, F. D., "Childhood Asthma and Wheezing Disorders," New England Journal of Medicine, vol. 349, no. 10, pp. 899–910, 2022.

6. Holgate, S. T., et al. "The Role of Allergic Inflammation in Chronic Airway Diseases," Allergy: European Journal of Allergy and Clinical Immunology, vol. 76, pp. 1213–1225, 2021.

7. Rusconi, F., et al. "Environmental Influences on Childhood Obstructive Bronchitis," Pediatric Pulmonology, vol. 57, no. 5, pp. 902–914, 2023.

8. Pavord, I. D., et al. The Eosinophilic Phenotype in Airway Diseases: Implications for Targeted Therapy. Lancet Respiratory Medicine, 2022.

9. National Asthma Education and Prevention Program. Expert Panel Report 4: Guidelines for the Diagnosis and Management of Asthma in Children, 2023.

10. Lötvall, J., et al. "Perspectives on Personalized Medicine in Allergic Diseases," Nature Reviews Immunology, vol. 21, pp. 557–569, 2022.

11. Gern, J. E., "The Interaction Between Viral Infections and Allergic Responses in Pediatric Patients," Journal of Allergy and Clinical Immunology, vol. 150, no. 2, pp. 341–355, 2022.

12. Soriano, J. B., et al. "Global Burden of Asthma and Related Allergic Diseases," The Lancet Global Health, vol. 9, no. 1, pp. 112–121, 2021.

13. Bosse, Y., et al. "Genetic Insights into Pediatric Asthma and Obstructive Bronchitis," American Journal of Respiratory and Critical Care Medicine, vol. 205, pp. 193–202, 2023.

14. The Global Initiative for Asthma (GINA). GINA Report 2023: Global Strategy for Asthma Management and Prevention.