CHANGES IN THE ORAL CAVITY CAUSED BY IODINE DEFICIENCY
Abstract
Iodine deficiency is a widespread issue affecting approximately one-third of the global population, particularly in regions where dietary iodine intake is insufficient. While its systemic impacts, such as hypothyroidism and goiter, are well-documented, its influence on oral health remains underexplored. This study investigates the specific changes in the oral cavity caused by iodine deficiency, including salivary gland dysfunction, mucosal atrophy, and increased susceptibility to infections. The findings emphasize the importance of early detection and comprehensive management strategies to mitigate these effects.
References
1. Hetzel BS, et al. "Iodine Deficiency Disorders (IDD) and Their Global Impact." Endocrine Reviews, 2009.
2. Zimmermann MB. "Iodine and Oral Health: A New Frontier." Clinical Oral Investigations, 2015.
3. World Health Organization. "Global Iodine Status in 2023: Progress and Challenges." WHO Press, 2023.
4. Kumar V, Abbas AK, Aster JC. "Thyroid Disorders and Oral Manifestations." 11th ed. Elsevier, 2023.
5. Li M, Eastman CJ. "The Changing Epidemiology of Iodine Deficiency." Nature Reviews Endocrinology, 2012.
6. Delange F. "Iodine Deficiency as a Cause of Brain Damage." Postgraduate Medical Journal, 2001.
7. Abraham GE. "The Importance of Iodine in the Human Body." Journal of Clinical Nutrition, 2006.
8. El-Tonsy AH, et al. "Salivary Gland Dysfunction in Systemic Disorders: A Focus on Iodine Deficiency." Journal of Oral Pathology and Medicine, 2010.
9. Sullivan KM, May S. "Impact of Iodine Deficiency on Health and Development: A Comprehensive Review." Public Health Nutrition, 2017.
10. Pearce EN, et al. "Iodine Deficiency and Its Effects on Thyroid Function and Oral Health." Thyroid Research and Practice, 2018.